TrueMethyl Solutions for Epigenetics

Product Highlights

Ovation® Ultralow Methyl-Seq Library Systems with TrueMethyl™ oxBS

The Ovation® Ultralow Methyl-Seq Library Systems provide a simple, fast and scalable solution for producing libraries used in conjunction with bisulfite sequencing to analyze DNA methylation.

  • With input amounts down to 10 ng the system enables methylation studies for a broad range of sample types and can be completed within 6 hours.  

Ovation® RRBS Methyl-Seq System with TrueMethyl™ oxBS

The Ovation® RRBS Methyl-Seq System provides a complete solution for producing Methyl-Seq libraries using the Reduced Representation Bisulfite Sequencing approach to analyze DNA methylation. 

  • Reduced Representation Bisulfite Sequencing or RRBS is a method that delivers genome-wide quantitative DNA methylation information without the need to sequence the entire genome.
  • Suitable sample input is human genomic DNA from a broad range of cell and tissue types.

TrueMethyl™ oxBS module

The TrueMethyl™ oxBS module contains the necessary reagents for quantification of the true level of cytosine methylation (5mC) and hydroxymethylation (5hmC).

  • Cost-effective, optimized analysis of both 5mC and 5hmC
  • Sensitive methylation detection from as little as 100 ng DNA
  • Streamlined protocol enables processing of 32 oxBS reactions and 32 BS-only reactions in <5 hours
  • Simple data analysis workflow and expert support

Targeted Methyl-Seq

COMING SOON!

For research use only. Not for use in diagnostic procedures.