GenomeWeb and NuGEN present Mechanisms of Imprinting: Identifying Parent-of-Origin Epigenetic Effects Webinar.

Jordi Moreno-Romero

In this webinar, Dr. Jordi Moreno-Romero will discuss the parent-of-origin epigenetic mechanisms that regulate seed development in plants, with a particular emphasis on differentiating the maternal or paternal origin of epigenetics marks. In plants, genomic imprinting occurs in the seed, particularly in the endosperm, an ephemeral tissue that supports embryo growth similarly to the nourishing role of the mammalian placenta. Dr. Moreno-Romero will discuss the findings of the study, which found that Polycomb-mediated H3 lysine 27 trimethylation (H3K27me3) is localized to DNA hypomethylated regions, linking DNA demethylation and H3K27me3 to imprinted gene expression.

Dr. Luke Sherlin will discuss current state of epigenetics research. Additionally, he will provide a brief overview of NuGEN's product solutions for this space. He will elaborate on the Ovation Ultralow Methyl-Seq System and Ovation RRBS Methyl-Seq System products and discuss the utility of RNA-Seq in epigenetic research.

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